In the Transcription-Coupled Repair Pathway of Nucleotide Excision Repair, How

In the transcription-coupled repair pathway of nucleotide excision repair, how is the presence of a lesion thought to be detected?

A) There are special enzymes that scan the DNA for such lesions.
B) The lesion may be signaled by a stalled RNA polymerase.
C) The lesion may be signaled by a stalled DNA polymerase.
D) The lesion may be signaled by a stalled peptidyl transferase.
E) The lesion may be detected single-stranded binding proteins.

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