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You Are Studying a Weasel and Find That Its Genome

Question 49

Multiple Choice

You are studying a weasel and find that its genome contains 7 Jκ and 55 Vκ genes. Other sources of variation (such as changes in the site at which a J sequence joins a V sequence and the ability of deoxynucleotidyl transferase to insert nucleotides at sites of strand breakage) have been found to introduce an additional ten-fold increase in variability. Assuming that any V sequence can join with any J sequence, how many different κ light chains can this organism make?


A) 620
B) 385
C) 3850
D) 70
E) 550

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