What Causes the Rhythmic Change in Cyclin Concentration in the Cell

What causes the rhythmic change in cyclin concentration in the cell cycle?

A) The changing ratio of cytoplasm to genome
B) The cascade of increased production once the protein is phosphorylated by Cdk
C) An increase in production of a Cdk once the restriction point is passed
D) Its destruction by an enzyme phosphorylated by the cyclin-Cdk complex
E) The binding of PDGF to receptors on the cell surface

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