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How Can Databases of Variants Be Used to Help Pinpoint

Question 10

Multiple Choice

How can databases of variants be used to help pinpoint a disease-causing mutation? (Select all that apply. )


A) Polymorphisms found in individuals that do not have the syndrome can be eliminated from consideration.
B) Common polymorphisms are unlikely to cause a rare disease and they can be eliminated from consideration.
C) Some amino acids are conserved in genes across species; mutations in conserved amino acids are not likely to cause disease.
D) Mutations that occur between genes are most likely to cause a genetic disease.

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