Some Evolutionary Biologists Argue That Changes in the Regulation of Genes

Some evolutionary biologists argue that changes in the regulation of genes rather than changes in the coding sequence are more likely to be involved in adaptation. Which of the following statements forms part of the basis for this argument?

A) Coding sequence changes are constrained because most genes perform multiple functions.
B) Regulatory mutations are more likely to occur than coding sequence mutations.
C) Regulatory changes likely affect all processes that a gene is involved in.
D) all of the above

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