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You Create Cells with a Version of the Origin Recognition

Question 42

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You create cells with a version of the origin recognition complex, ORC, that cannot be phosphorylated by S-Cdk and thus cannot be inactivated.Which of the following statements describes the likely consequence of this change in ORC?


A) Cells will enter S phase prematurely.
B) Cells will replicate some regions of the genome more than once in a cell cycle.
C) ORC will be unable to bind to DNA.
D) DNA helicases will not be able to open up the double helix at the replication origin.

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