Consider a Description of an Enzymatic Reaction Pathway That Begins

Consider a description of an enzymatic reaction pathway that begins with the binding of substrate S to enzyme E, and ends with the release of product P from the enzyme.
E + S → ES → EP → E + P
In many circumstances,
K_m = [E][S]/[ES]
A.What proportion of enzyme molecules is bound to substrate when [S] = K_m?
B.Recall that when [S] = K_m, the reaction rate is ½V_max.Does your answer to part A make sense in the light of this rate information?

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