Penicillin Kills Bacteria by Inhibiting the Biosynthesis of the Cell $\beta$

Penicillin kills bacteria by inhibiting the biosynthesis of the cell wall. How does penicillin cause the inhibition?

A) The transpeptidase of the bacteria binds to methicillin.
B) The carbonyl carbon of the $\beta$ -lactam ring of penicillin binds to transpeptidase.
C) The $\beta$ -lactam ring in penicillin is hydrolyzed.
D) The glycine in transpeptidase binds to penicillin.

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