Orlistat and Olestra Can Both Lead to Undigested Lipids in the Colon

Orlistat and olestra can both lead to undigested lipids in the colon, yet they do so by contrasting mechanisms. Orlistat __________, whereas olestra _.

A) inhibits pancreatic lipase; activates PPAR $\gamma$
B) inhibits pancreatic lipase; is a fat substitute that is not a substrate for pancreatic lipase
C) is a fat substitute that is not a substrate for pancreatic lipase; inhibits pancreatic lipase
D) activates PPAR $\gamma$ ; inhibits pancreatic lipase

Correct Answer:

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