An Enzyme Has a Total of Four Active Sites

An enzyme has a total of four active sites. When you denature the molecule and study its composition, you find that each active site occurs on a different polypeptide. Which of the following hypotheses does this observation support?

A) The enzyme requires a cofactor to function normally.
B) The protein's structure is affected by temperature and pH.
C) The enzyme is subject to allosteric regulation.
D) The protein has quaternary structure.

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