Some Cancerous Tumors Act Like Endocrine Glands, Causing Disturbances in Electrolyte

Some cancerous tumors act like endocrine glands, causing disturbances in electrolyte balance. What might be the result of very high calcium levels in interstitial fluid?

A) Muscle and nerve cells would require less stimulation to depolarize.
B) Muscle and nerve cells would require more stimulation to depolarize.
C) Depolarization of muscle and nerve cells would not be affected by extra calcium outside the cells.
D) Muscle and nerve cell function could only be affected by changing levels of sodium and potassium.

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