Individuals Who Fail to Express Functional Bruton's Tyrosine Kinase Exhibit

Individuals who fail to express functional Bruton's tyrosine kinase exhibit all of the following characteristics except

A) B-cell development is blocked at the immature B-cell stage.
B) They are usually male because the Btk gene is on the X chromosome.
C) They suffer from an immune deficiency known as X-linked agammaglobulinemia (XLA) .
D) Recurrent infections with extracellular bacteria are common.
E) They benefit from treatment with immunoglobulin infusions.

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