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The Table Below Lists Several Genotypes Associated with the Lac \quad

Question 57

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The table below lists several genotypes associated with the lac operon in E.coli.For each,indicate with a "+" or a "-" whether ?-galactosidase would be expected to be produced at induced levels.
\quad \quad \quad \quad \quad \quad \quad \quad \quad \quad \quad \quad \quad \quad \quad B-Galactosidase Production \text { B-Galactosidase Production }
 Genotype  No Lactose  With Lactose  (a) I+O+Z+/F′I−O+Z+ (b) I−OcZ−F′I−OcZ− (c) I−OcZ+/F′I−O+Z+ (d) Is Oc Z-/F’ Is O+Z+\begin{array}{lccc}\text { Genotype }& \text { No Lactose } &\text { With Lactose } \\\hline \text { (a) } I+O+Z+/ F^{\prime} I-O+Z+\\\text { (b) } I-O c Z-F^{\prime} I-O c Z-\\\text { (c) } I-O c Z+/ F^{\prime} I-O+Z+\\\text { (d) Is Oc Z-/F' Is } O+Z+\\\end{array}

I+= I^{+}= wild-type repressor
I I - = mutant repressor (unable to bind to the operator)
Is= \mathrm{I}^{s}= mutant repressor (insensitive to lactose)
O+= \mathrm{O}^{+}= wild-type operator
Oc= \mathrm{O}^{c}= constitutive operator (insensitive to repressor)

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