Question 1

A typical flow of information in a signal transduction pathway would be which of the following?&#10;A)Receptor $\rightarrow$ G protein $\rightarrow$ second messenger $\rightarrow$ biological response&#10;B)Hormone $\rightarrow$ second messenger $\rightarrow$ G protein-coupled receptor (GPCR)$\rightarrow$ biological response&#10;C)Hormone $\rightarrow$ second messenger $\rightarrow$ GPCR&#10;D)Hormone $\rightarrow$ receptor $\rightarrow$ second messenger $\rightarrow$ GPCR $\rightarrow$ biological response&#10;E)GPCR $\rightarrow$ second messenger $\rightarrow$ biological response

Accepted Answer

Receptor $\rightarrow$ G protein $\rightarrow$ second messenger $\rightarrow$ biological response&#10;

Question 2

Molecules that are produced by cells and act locally on other cells are called:&#10;A)Steroid hormones.&#10;B)Receptors.&#10;C)Paracrine hormones.&#10;D)Phosphatases.&#10;E)Iodothyronines.

Accepted Answer

C

Question 3

The negative side effects of nonsteroidal antiinflammatory drugs (NSAIDs)on the cardiovascular system are mediated by inhibition of which enzyme?&#10;A)Cyclooxygenase-1 (COX1)&#10;B)$\gamma$-Secretase&#10;C)Presenilin 1&#10;D)Cyclooxygenase-2 (COX2)&#10;E)Adenylate cyclase

Accepted Answer

Cyclooxygenase-2 (COX2)&#10;

Question 4

In the following list,which drug is correctly used to treat the disease listed?&#10;A)$\beta$-Adrenergic receptor agonists with depression&#10;B)Fluoxetine (Prozac)with low blood pressure&#10;C)Trastuzumab (Herceptin)with metastatic HYPERLINK &#34;http://en.wikipedia.org/wiki/Colorectal_cancer&#34;colorectal cancer&#10;D)Sildenafil (Viagra)with pulmonary arterial hypertension&#10;E)Cetuximab (Erbitux)and bevacizumab (Avastin)with metastatic breast cancer

Accepted Answer

The answer of In the following list,which drug is correctly...

Deck 3: Signal Transduction, membrane Receptors, second Messengers, and Regulation of Gene Expression